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Patients: Adults 18 years eligible for anti-obesity medication

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Metformin and Resveratrol Inhibit Drp1-Mediated Mitochondrial Fission and Prevent ER Stress-Associated NLRP3 Inflammasome Activation in the Adipose Tissue of Diabetic Mice

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Once bound to the antioxidant response element (ARE), Nrf2 upregulates cytoprotective genes such as Heme Oxygenase-1 (HO-1) and NAD(P)H: Quinone Oxidoreductase 1 (NQO1) (Kim et al., 2017
