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Diabetes 49 , 17311739 (2000)
Lancet Diabetes Endocrinol 6(8):605617 [DOI] [PubMed] [Google Scholar] Tuttle KR, Lakshmanan MC, Rayner B, Busch RS, Zimmermann AG, Woodward DB et al (2018b) Dulaglutide versus insulin glargine in patients with type 2 diabetes and moderate-to-severe chronic kidney disease (AWARD-7): a multicentre, open-label, randomised trial
The deeper story, supported by emerging research, is that NAD+ may be upstream of GLP-1 production entirely
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These findings offer a mechanistic foundation for exploring GLP-1RAs as novel anti-inflammatory therapies in IBD, bridging gut physiology with immune modulation
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