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Probiotic Strains: Strain Role Lactobacillus acidophilus Small intestine colonizer, lactose metabolism support Lactobacillus casei Immune modulation, carbohydrate fermentation Lactobacillus plantarum Gut barrier integrity, anti-inflammatory

Moreover, the efficacy of these drugs in MC4R KO mice aligns with clinical studies, indicating that MC4R KO mice serve as a reliable animal model for obesity research.

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