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Alcohol is calorie-dense, can worsen nausea (a common side effect of incretin therapies), and may increase the risk of hypoglycaemia in individuals also taking insulin or sulphonylureas

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In the presence of compound 2, both GLP-1 and the ECD moved inwards to the TMD core by 0.7 and 1.3 (measured at the C of Y19 in GLP-1 and P90 in ECD), respectively

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Therefore, the findings may not apply to tirzepatide

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The WHO first released its list of essential medicines in 1977

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