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it cannot be marketed or used as a medicine

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[DOI] [PubMed] [Google Scholar] 69.ONeil PM, et al

We outline new mechanistic concepts, future therapeutic opportunities, potential for differentiation from currently available medicines and areas of uncertainty requiring additional investigation

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Nonetheless, metformin use has been associated with changes in the abundance of specific bacterial genera in the gut microbiota, and this has centered on the enrichment of A