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Some GLP-1 users, particularly those focused on high-protein, low-fat diets , inadvertently reduce fat intake to levels that contribute to constipation
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PubMed CrossRef Yin J, Ma T, Li J, et al

Running on mixed fuel-dual agonistic approach of GLP-1 and GCG receptors leads to beneficial impact on body weight and blood glucose control: a comparative study between mice and non-human primates

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Additionally, gastrointestinal side effects are most pronounced during the first two weeks at a new dose and typically improve by weeks three and four
