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doi:10.1001/jama.295.13.jpc60002 Jensen JK, Zobel EH, von Scholten BJ, et al

An oral formulation of a GLP-1RA represents a useful option to help improve acceptance and adherence compared with injectable formulations in those patients with a preference for oral therapy, and it may lead to earlier initiation of these agents in the continuum of the disease

However, while on a GLP-1, one of the concerns that often arises is muscle loss

Tirzepatide, as a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist, offers a unique mechanism of action that targets multiple pathways involved in glucose and energy metabolism

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The June study examined a total of 139,002 patients with diabetes, which included a group of 46,334 patients who had taken GLP-1RAs and a group of 92,668 who had not