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Indianapolis, IN: Eli Lilly and Co

doi: 10.2337/dc12-2454 [DOI] [PMC free article] [PubMed] [Google Scholar] 217

For patients planning pregnancy, semaglutide should be discontinued at least 2 months before a planned pregnancy due to the long half-life, while tirzepatide may persist for approximately 1 month

However, long-term efficacy and safety remain to be established, especially concerning metabolic disturbances in advanced disease stages

Statements Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

Important Note Persistent vomiting, severe abdominal pain, or symptoms of pancreatitis require immediate medical evaluation