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10.7150/ijbs.59965 [DOI] [PMC free article] [PubMed] [Google Scholar] 119.Hamal S, Cherukuri L, Shaikh K, Kinninger A, Doshi J, Birudaraju D, et al

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Desensitization and Receptor Trafficking Most agonist-activated GPCRs undergo rapid desensitization through a coordinated two-step process: first, phosphorylation of the receptor by GRKs, and second, recruitment of -arrestins to these phosphorylated sites, which sterically block further G-protein coupling [54]

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