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GLP-1RAs may be appropriate in patients with a BMI of 25 or greater and does require a rigorous prospective study to further characterize the role of GLP-1RAs in the treatment of lymphedema
10.1056/NEJMoa1706442 14
More research is needed in this area
A meta-analysis of 21 trials showed weight loss of 0.2 to 7.2 kg with GLP-1RAs, with higher doses leading to greater weight loss
Semaglutide is a medication primarily used to treat type 2 diabetes and, more recently, for weight management in certain patients
Next, only 2 studies were eligible for inclusion in the indirect treatment comparison, which may limit the robustness of the comparison
