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2023 Diabetic kidney disease fact sheet in Korea

Hyperleptinaemia A condition in which leptin levels in the blood are elevated, typically in obesity

While additional research is needed to address knowledge gaps with dietary supplementation in this population, current recommendations can be provided based on evidence from the populations with obesity, traditional dieting and weight loss, bariatric surgery interventions, and adiposity-related complications

Metalloproteinases are extracellular matrix remodeling enzymes, and any change in their regulatory mechanism may contribute to complications in T1DM 42

In this sense, they may be thought of as disease-modifying agents instead of glucose-lowering therapy

LH, Luteinizing hormone