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Any history of Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

Retatrutide is an investigational synthetic peptide studied for its unique triple receptor agonist mechanism involving GLP-1, GIP, and glucagon receptors

Thus, prevention strategies, including nutritional intervention and safe exercise prescriptions, should be emphasized in patients with type 2 diabetes who have started on semaglutide

Although baseline and month-6 between-group differences were small, the magnitude of reduction over time was significantly greater in the semaglutide group ( p = 0.001), with a large effect size (d = 0.99) (Table 2)

Piggybacking off Cleveland Clinic's stance, the benefits of GLP-1 meds are likely to outweigh the risks for individuals with type 2 diabetes and obesity and NOT for vanity-driven users who solely want to quickly drop a few pounds for an upcoming event

I can't wait to start seeing the results