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Tirzepatide (Mounjaro/Zepbound) achieves the greatest weight loss at 20.9%, followed by semaglutide 2.4mg (Wegovy) at 14.9%, then liraglutide 3.0mg (Saxenda)...

References: Abbass et al., AJO 2025

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GLP-1 receptor agonists (semaglutide, liraglutide, tirzepatide) act on the brain as well as the gut, and a 2026 real-world cohort study from Kamel-Abusalha et a

Both disease entities are characterised by complex and heterogeneous clinical spectra linked to distinct symptoms and organ systems which, on a first glimpse, do not have many commonalities in clinical practice

They also draw on their clinical experience to discuss and advise on the management of augmentation induced by dopaminergic drugs.