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The logic behind this approach is that the concomitant activation of GLP1 and estrogen receptors may drive additional favorable effects, when compared with the individual activation of these pathways, which are known to conduct, on their own, beneficial metabolic actions on energy and glucose homeostasis 52
E.MillerH.GonzalezA.McDonaldD.et al

5,6 Nutrients associated with GLP1 secretion are monosaccharides, long-chain fatty acids and short-chain fatty acids (from bacterial fiber fermentation)

doi: 10.1016/j.molmet.2024.101880 244 Re CecconiADBaroneMFortiMLunardiMCagnottoASalmonaMet al

These metabolites interact with L-cells in your intestinal lining, which are the cells responsible for producing GLP-1

For Weekly Injections (Semaglutide/Tirzepatide): There's a bit of flexibility built in
