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Elucidating mechanisms of action in relation to cardiorenal protection Questions remain about the mechanism of action of SGLT2 inhibitors and GLP-RAs, particularly in relation to the cardiorenal benefits observed in some diabetes CVOTs [110112] (Additional file 2: Fig

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Wegovy, an innovative weight loss drug for non-diabetics, harnesses the power of its active ingredient, semaglutide

Polypharmacy considerations are particularly relevant in the patient populations typically prescribed semaglutide

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This leads to uncertainty behind the actual mechanism of Akkermansia supplementation, as far as whether Akkermansia actually stays in the body when administered, whether supplementation has only temporary or long-lasting effects, and if supplementation can aid the natural composition of Akkermansia or not