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Leptin activates TRPC channels to depolarize steroidogenic factor 1 (SF1) neurons in the VMH, and thus maintains energy balance and glucose homeostasis [142]

Studies in AD models have also demonstrated reduced amyloid aggregation in various brain regions (Teixeira et al

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Starting an FDA-approved weight loss program early can dramatically reduce these risks before they become unmanageable

doi: 10.1016/s0015-0282(16)49574-9

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