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With no current approved treatments for this conditionwhich affects millions worldwidethese results could mark a turning point for patients suffering from this often silent but deadly disease.

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Recombinant CHO-K1 cells stably overexpress human glucagon-like peptide-1 receptor (GLP1R) on the surface and contain high levels of G protein Gs to couple with the receptor in downstream signaling pathways.

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These drugs mimic the effects of the naturally occurring GLP-1 hormone, which is produced in the small intestine and plays a crucial role in regulating insulin secretion, glucose homeostasis, and appetite.

Multi-axis metabolic peptide signaling