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The beneficial effect of TZT in T2DM and obesity is related to direct activation of GIP and GLP-1 receptors with subsequent improvement of insulin sensitivity and reduction of body weight

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Glucagon-like peptide-1 (GLP-1) is a member of the proglucagon incretin family implicated in the control of appetite and satiety

With GLP1 therapeutics entering their second wave of innovation, this is a pivotal moment for teams pushing boundaries in metabolic and neuroendocrine drug development