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Description
6 Safety and tolerability 6.1 Adverse events reported in clinical trials Tirzepatide offers therapeutic benefits and demonstrates a safety profile comparable to that of other incretin-based therapies, such as semaglutide and dulaglutide (Jung and Jung 2022)
PMID 34310013 Wilding JHH et al
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Semaglutide improves insulin sensitivity through its mechanisms
JAMA, 2014
In humans, a landmark 2023 observational study of over 80,000 patients with obesity found that those on semaglutide had a 50-56% lower incidence of alcohol use disorder compared to patients on other anti-obesity medications
