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Weight loss results were slightly lower in the diabetes population (16.9% at the highest dose versus 24.2% in the obesity trial), but glycemic improvements were substantial

Characterization of reproductive, metabolic, and endocrine features of polycystic ovary syndrome in female hyperandrogenic mouse models

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By the end of the 68-week trial, participants taking Wegovy saw an average decrease of 16.1 percentage points in their BMI percentile compared with the placebo group, whose average BMI percentile increased by 0.6 percentage points

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In addition to improving insulin resistance, a hypothesized mechanism in the progression of PD, in vitro and in vivo studies have shown that GLP-1 RAs can inhibit many pathways present in the pathogenesis of PD