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For example, liraglutide, a GLP-1 receptor agonist, improved cognitive function in n = 19 patients with major depressive disorder (MDD) or bipolar disorder in a pilot randomised controlled trial (RCT) [16], whilst a systematic review and meta-analysis reported a pooled reduction in depressive symptoms with GLP-1 receptor agonists compared to other antidiabetic therapies [17]

From gut microbiota through low-grade inflammation to obesity: Key players and potential targets

[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Garcia-Bailo B, Toguri C, Eny KM, El-Sohemy A

Patients beginning semaglutide injection therapy while on blood thinners should inform their prescriber and discuss timing of INR checks (for warfarin users) or ongoing monitoring protocols to ensure therapeutic stability