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Ex-4 significantly reduces neuroinflammation by converting proinflammatory M1 microglia into anti-inflammatory M2 microglia both in vitro and in vivo through the rescue of the expression of Arf and Rho GAP adapter protein 3 (ARAP3)

Common side effects include nausea, vomiting, diarrhoea, constipation, and abdominal discomfort, particularly during the initial titration phase
At 52 weeks, the change in HbA1c from baseline was superior for semaglutide as compared with liraglutide (0.3% [95% CI: 0.4%, 0.1%])
[DOI] [PubMed] [Google Scholar] 119.Gasbjerg LS, Bari EJ, Stensen S, Hoe B, Lanng AR, et al
