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Chronic Pain : One of the most debilitating long-term effects of chronic pancreatitis is persistent abdominal pain

Response rates vary by molecule newer agents such as tirzepatide and semaglutide yield higher responder rates (~86%91%) than older agents such as exenatide or liraglutide (~40%65%) (223) and vary by baseline BMI, sex, and glycemic status, with women and individuals with higher BMI responding better (222, 224)

2), and were not significantly different in a meta-analysis of 189 patients with T2DM and 217 healthy controls [19]

The reasons people do not lose weight on semaglutide are usually different from the reasons phentermine fails, which is why cross-class switching can produce different outcomes