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Looking toward the future The wheels of progress on multi-agonists, oral small molecules, and tissue-targeted approaches are moving forward at breakneck speed

These studies offer strong evidence for the clinical potential of GLP-1RAs in cardiovascular care

In line with this observation, our laboratory found that a brain infusion of exendin-9, an antagonist of the GLP-1 receptor, can reduce muscle glucose utilization and its storage as glycogen in mice receiving glucose from an intragastric catheter [70]

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Addressing the Epidemic: Insulin Resistance and Metabolic Disease Insulin resistance and metabolic syndrome are central to a global health crisis affecting billions

Patients consistently report significant improvements in cardiovascular health, with reduced blood pressure, improved cholesterol profiles, and enhanced heart function