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Sentongo TA, Semeao EJ, Piccoli DA, Stallings VA, Zemel BS
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It has also been demonstrated that inhibitory GABAergic CNS GIPR + neurons are necessary for the food intake reducing effects of GIPR agonists and dual incretin co-agonists (54, 55), while excitatory glutamatergic CNS GLP-1R + neurons are necessary for the food intake reducing effects of GLP-1R agonists (71)
The results revealed no significant difference in the odds ratios in most subgroups for patients in the metformin-GLP-1 RA subgroup versus those in the metformin-oADM subgroup, except for the subgroup aged 55 years
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