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Our results show that weight loss though GLP-based therapies is associated with a significant reduction in 24-hour urine oxalate, urine sulfate, and urine ammonium concentrations, along with nonsignificant changes in other 24-hour urine parameters relevant to stone formation

That last point is easy to miss

"GLP-1 medications represent the chance for a breakthrough in obesity treatment, but to unlock this potential, more patients need access to them plus the care and coaching that makes treatment most effective

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Those that are already depressed at baseline may also be overweight and obese and thus take Ozempic to lose weight

thus therapies that address both liver and cardiovascular risk are highly desirable