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Others operate in regulatory grey zones with minimal quality control

Once-weekly sema in adults with overweight or obesity

31 As such, GLP-1 RAs and dual GLP/GIP-RAs have emerged as essential drugs for the treatment of patients with type 2 diabetes and, more recently, for the management of weight loss in the absence of diabetes

Moreover, a meta-analysis of cardiovascular outcomes in trials of GLP-1RAs has revealed cardiovascular benefits in T2D patients with or without pre-existing cardiovascular diseases [4]