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The bioavailability of policosanol is limited, and additional studies are needed to determine if policosanol is active in the liver

It requires medical expertise

This histologic improvement is vital for managing MASH, as it can prevent the progression to more severe liver diseases

Patients with a history of or current diagnosis of certain conditions may not be candidates even if they otherwise qualify

While this may provide a marginal additional calorie burn, the primary benefit of the ice gelatin trick remains the gelatin itself and its amino acid content

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