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January 2024: CBS News reported that in the FDAs January through March 2024 FAERS potential-safety-signals report, GLP-1 receptor agonists were listed for a potential signal (dysaesthesia)
The bulkier proline occupies more of the S1 pocket than does alanine, which explains the higher affinity for peptides with proline versus alanine at the second position
When used in combination with a sulfonylurea, metformin, or both, exenatide produces a decrease in A1C of less than 1 percentage point
This partnership is key to long-term success
2023 Jun 23-26
Courcoulas AP, Christian NJ, Belle SH, Berk PD, Flum DR, Garcia L, Horlick M, Kalarchian MA, King WC, Mitchell JE, Patterson EJ, Pender JR, Pomp A, Pories WJ, Thirlby RC, Yanovski SZ, Wolfe BM
