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They were also more likely to have metabolic syndrome

Nausea is typically worst in the first few days following a dose increase

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21 Headache outcomes may show more benefit over a longer trial duration, as during the relatively short time horizon of this trial other factors may also have contributed to headache such as medication overuse and opiate use, which occur in approximately one-third of IIH patients

For instance, the administration of GLP-1 nanomedicine resulted in a decrease in IL-1, a pro-inflammatory cytokine, and a marked improvement of the architecture of the intestinal epithelium in a colitis model [223]