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Key points for incorporating exercise include: Patient experiences with Wegovy for weight management have been varied, reflecting diverse individual reactions to the medication

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doi:10.1016/j.amjmed.2025.01.021 Meloni AR, DeYoung MB, Lowe C, Parkes DG

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Furthermore, the deletion of Bmal1 in the brain induced apoE expression (inhibiting, e.g., astrocytic clearance of A [73]), potentially elucidating how circadian disruption may increase A burden in the brain