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David Risinger, a senior managing director and senior research analyst covering diversified biopharmaceuticals with Leerink Partners, and three colleagues called the results from ATTAIN-2 compelling, and maintained an earlier prediction that orforglipron will attain sales that more than reach multi-billion-dollar blockbuster heights

New research shows that GLP-1 receptors exist throughout the body, particularly in areas outside the pancreas and including the central nervous system, cardiovascular system, and immune cells [4,5]

Incretin-based therapies in obesity-related kidney disease In recent years, studies have been expanded to investigate the effects of incretin-based therapies on kidney outcomes in overweight/obese individuals without T2D

Rev Colomb Gastroenterol

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In this model of PD, DA-JC1, a dual GLP-1/GIP receptor agonist, improved Akt activation [138], and levels of pAkt were increased by exendin-4 and another dual GLP-1/GIP agonist, DA5-CH [131]