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However, retatrutide, as a multi-receptor agonist, may have broader effects on metabolism and potentially unique side effects as clinical trials continue to uncover its full profile

People using insulin, sulfonylureas, or other glucose-lowering medicines may need closer glucose monitoring during appetite changes
Thus, think of milk alkali in patients who have a metabolic alkalosis with hypercalcemia

63 Both GLP-1RA and SGLT2-I offer minimal risk of hypoglycemia and appear to have positive, although modest, effects on weight and BP
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Patients who gained weight easily before treatment often find the same occurs after stopping, unless lifestyle modifications persist independently
