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Obesity (PMC), 2025

The involvement of GLP-1 in PD can be simplified to the activation of the MAPK/extracellular signal-regulated kinase 1/2 (ERK) pathway, which has an important role in synaptic plasticity, and the PI3K/Akt pathway signaled by GLP-1 receptor stimulation and the subsequent increase in cAMP and PKA and PI3K activation [73]

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Numerous studies have substantiated the significant impact of semaglutide on blood sugar management in individuals with type 2 diabetes

Wegovy is FDA-approved for weight loss and dosed up to 2.4 mg per week
