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The mean duration of type 2 diabetes mellitus was 2.4 years, mean HbA1c was 8.0%, mean weight was 97 kg, and the mean baseline BMI was 35 kg/m2

The clinical importance of these potential relationships necessitates systematic evaluation

Therefore, given the emerging evidence for non-anatomic contributors to OSA pathophysiology, as well as the advent of anti-obesity pharmacotherapy [16], the therapeutic landscape for the personalized management of OSA has evolved over the last decade

A research article on the effectiveness and safety of the non-peptide glucagon-like peptide- 1 (GLP- 1) receptor agonist Orforlipron than once daily oral therapy for weight reduction in adults with obesity

Side effects are more common when you are first starting treatment or moving up to a higher dose

Gradual dose increases can help minimize discomfort