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Maintenance phase (week 13+): Target maintenance doses in the trials were 4 mg, 8 mg, and 12 mg once weekly

Based on these results, Strecker said their institution made changes to the preoperative instructions for patients taking GLP-1 agonists prior to THA

40 Reasons for discrepancies in magnitudes of effect could be that trial participants were generally enrolled with a higher baseline HbA1c, higher level of dysregulation, and longer diabetes duration, which could cause higher absolute differences between baseline achieved HbA1c levels at the end of the trial

Increasing the dose of tirzepatide slowly helps your body adjust to the medication