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Glucagon is usually thought of as a glucose- raising hormone, but in the context of simultaneous GLP-1/GIP agonism the net effect studied in trials was increased energy expenditure alongside strong glycemic control a combination that appears to explain the outsized weight effect observed in the research

Brand name GLP-1s like Ozempic, Trulicity, and Victoza (among others) have long been used in the treatment of type 2 diabetes specifically

First, we did not require patients to continuously take a GLP-1 RA for a pre-specified amount of time before discontinuation

doi: 10.1001/jama.2024.5003

(NIDDK) This is why calling them just appetite suppressants misses the point

Those with Hyperthyroidism, Glaucoma, Peptic Ulcer Disease, Prostatic Hypertrophy, Cardiac Disease, or Epilepsy should avoid taking Phentermine as well