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Learn what evidence shows about colorectal cancer risk.

Nonalcoholic fatty liver disease (NAFLD) is a prevalent metabolic liver disease closely associated with the epidemics of obesity and type 2 diabetes mellitus (T2DM), but without licensed pharmacological treatment to date

Among these effects, increased insulin sensitivity, either by direct action on target organs or secondary to weight loss, might act synergistically with enhanced beta-cell function and insulin upregulation in the pancreas, collectively improving metabolic control.