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They seek it out because something fundamental has changed in how their body regulates energy, hunger, and metabolism

Continued treatment with tirzepatide for maintenance of weight reduction in adults with obesity: the SURMOUNT-4 Randomized Clinical Trial

Miyazaki M, Flowers MT, Sampath H, et al

Katherine Saunders, an internal medicine specialist with Weill Cornell Medicine in New York City

The combination of these effects could provide meaningful metabolic support even if GLP-1 increases remain minimal

Hormones, metabolism and appetite signals all influence how the body responds to food and weight loss
