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Among patients with obesity, semaglutide 7.2 mg reduced body weight by more than 18% for those without diabetes and by more than 13% for those with diabetes, according to the results of the STEP UP and STEP UP T2D trials

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Updated March 2026.

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Peptide: Retatrutide 20mg Type: Longevity Brand: Bio Stem (For research purposes only) Retatrutide is known as a triple agonist, meaning it activates:GLP-1 receptors helps control appetite + slows digestionGIP receptors improves insulin response + nutrient handlingGlucagon receptors increases energy expenditure + fat burning Retatrutide is a multi-receptor agonist currently being studied for its interaction with metabolic pathways, including GLP-1, GIP, and glucagon receptors