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Contact your GP or diabetes specialist if you experience : Persistent vomiting that prevents you from keeping down food, fluids, or other medications for more than 24 hours Signs of dehydration , including dark urine, dizziness, extreme thirst, dry mouth, or reduced urination Abdominal pain , particularly if constant, sharp, or radiating to your back (potential pancreatitis) Nausea that significantly worsens rather than improves over time Inability to maintain adequate nutrition or unintended weight loss exceeding clinical targets Symptoms of hypoglycaemia (low blood sugar) if taking Ozempic alongside insulin or sulphonylureasshakiness, confusion, sweating, rapid heartbeat [1] [4] Right upper abdominal pain, fever, or yellowing of skin/eyes , which could indicate gallbladder disease (a known risk with GLP-1 receptor agonists) Seek immediate medical attention (call 999 or attend A&E) if you develop : Severe, persistent abdominal pain with vomiting (possible pancreatitis) Signs of allergic reactionfacial swelling, difficulty breathing, severe rash Symptoms of diabetic ketoacidosisexcessive thirst, frequent urination, confusion, fruity-smelling breath (particularly relevant if you use insulin or during intercurrent illness

Dehydration can sneak up on you and make you feel sluggish, which is the last thing you need when youre trying to lose weight

Diabetologia 59 , 25882593 (2016)

They offer cost-effective treatment options because they can self-amplify and autonomously produce therapeutic agents

Staying hydrated is essentialdehydration amplifies nausea

How GLP-1 Receptor Agonists and SGLT2 Inhibitors Work Together Benefits of Combining GLP-1 and SGLT2 Inhibitor Treatment Who Is Suitable for GLP-1 and SGLT2 Inhibitor Combination Therapy