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however, this has not been a consistent finding within a meta-analysis

Usui T, Kajita K, Kajita T, et al

Diabetes Care (2014) 37:19107

Lastly, the systemic effects of GLP-1RAs, such as body weight loss [103] and potential reduction in muscle mass [104], pose significant challenges for elderly individuals with neurodegenerative diseases

Clinical trials show average weight loss of 10-22% of body weight over 68 weeks, depending on starting weight and adherence

Alzheimers disease pharmacotherapy in relation to cholinergic system involvement
