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24 This can be due to differences in the specific drug used, the dosage, the duration of the study, the characteristics of the participants (age, baseline health) 9 , the methods used to measure body composition (DXA, BIA, MRI all have different strengths and weaknesses) 16 , and whether interventions like dietary counseling (especially protein emphasis) and exercise were included
medRxiv 2021.03.22.21252507 (Preprint)
Dose, delivery, and brain absorption matter: Some GLP-1s are better absorbed and have more potential to improve cognitive endpoints than others Combination therapeutics may be required: GLP-1s may need to be paired with lifestyle interventions or complementary neuroprotective agents to produce measurable results in specific disease outcomes
Proper medical assessment, prescribing, and monitoring are essential
The goal is getting 25-30g protein even if you're not hungry
Chemical analogues of GLP-1 are currently approved for the treatment of type 2 diabetes (T2D) and obesity 3,4
