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Groundbreaking clinical trials published in late 2023 and 2024 show that semaglutide, approved in 2019 for treating diabetes and in 2021 for weight management, also reduces rates of heart disease and kidney disease, and reduces tissue and systemic inflammation

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Endocrinology, Diabetes & Metabolism Case Reports, 2025 (3), e250065

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This mechanism makes semaglutide valuable for diabetes management even when weight loss is modest