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In FLOW, semaglutide improved kidney outcomes in patients with type 2 diabetes and chronic kidney disease. What GLP-1 and GLP-1/GIP Medications Do Not Do 1) They Do NOT Treat Autoimmune Disorders Autoimmune diseases involve immune-system pathways such as T-cell activation, autoantibody production, complement activation, and immune cytokine dysregulation

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Raising unmodified GLP-1 levels improves pancreas functioning

However, several concerns remain