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Description
Combining glucagon-like peptide 1 receptor agonists and sodiumglucose cotransporter 2 inhibitors to target multiple organ defects in type 2 diabetes
Suzuki Y, Nakamura N, Miyabe M, et al
In both patient populations with pre-existing cardiovascular disease, DPP-4 inhibitors are recommended as one possible third-line therapy besides SGLT-2 inhibitors, thiazolidinediones, or insulin, when therapeutic goals are not met with the previous dual combination
Unless you also adopt effective diet changes
doi: 10.2147/AHMT.S383454
To examine molecular mechanisms of this phenomenon, exendin (939)specific inhibitor of GLP-1 receptor, Rp-cAMPthe cAMP inhibitor, PI3 K inhibitor LY294002 or p44/42 mitogen-activated protein kinase inhibitor UO126, were given concomitantly with GLP-1 + VP infusion
