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Nausea is by far the most commonly reported symptom and tends to appear early, especially during dose increases. Vomiting, diarrhea, and constipation can also occur, though their frequency depends on the specific medication and dose

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[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Marso SP, Bain SC, Consoli A, et al

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[DOI] [PubMed] [Google Scholar] 84.McMorrow HE, Lorch CM, Hayes NW, Fleps SW, Frydman JA, Xia JL, et al