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Eli Lilly: Tirzepatide/Mounjaro Lily initially developed Tirzepatide as a dual agonist, with a half-life of around 5 days, for the treatment of T2DM

The goal is finding your therapeutic sweet spotthe dose where you see consistent weight loss and improved hunger control without intolerable side effects

the rest are a minor concern but not a deal-breaker

Whilst these effects might appear complementary, the combined hormonal and metabolic signalling could produce effects that are difficult to monitor or predict without clinical oversight

They bring an extra 2 grams of protein and 4 grams of fiber to the table

The peptide dosing guide explains why gradual titration matters for all peptide protocols, not just tirzepatide