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Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: A randomised controlled trial

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PLoS ONE (2017) 12:e0189060

It is also synthesized in the brainstem and acts as a neuromodulator within key regions involved in reward processing, stress regulation, and executive function

But if you ask the Americans who have ever used GLP-1s themselves, many feel positively about both the long-term impact of the drugs and the effect the drugs will have on obesity in the nation.

And what does it mean for stakeholders across the industry