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Indirect Effects The indirect effects of the use of GLP-1 and GIP/GLP-1 receptor agonists on the lung are probably mediated by weight loss and improved lung mechanics

Thus, in the present study, we wanted to test whether GLP-1R agonist, liraglutide could alleviate inflammation by activating the PKA/CREB pathway in a rat model of knee OA induced by MIA, which might provide therapeutic candidate for the clinical management of OA

doi:10.1016/j.tem.2015.05.007 59

Ease of entry matters as much as breadth of content

This format diversity is practically significant: most platforms in this review series offer only injectable compounded GLP-1s, and the few that offer oral formats typically offer only one alternative